SEMAGLUTIDE（10 VIALS / BOX）
Synthetic Peptide for Metabolic Pathway Research
Technical Overview
Semaglutide 20mg is a synthetic peptide compound developed for laboratory research involving incretin signaling and GLP-1 receptor pharmacology, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying receptor-agonist binding profiles, downstream cAMP and insulinotropic signaling responses, and related biochemical mechanisms.
Semaglutide is a long-acting GLP-1 receptor analog featuring an Aib substitution at position 2 to confer DPP-IV resistance and a fatty-acid (C18 diacid) side chain at Lys26 that promotes albumin binding for extended plasma residence. In research models, it is investigated as a tool compound for probing GLP-1R conformational dynamics and beta-arrestin recruitment.
Investigators commonly use this analog to dissect incretin-axis signaling in pancreatic islet preparations, hypothalamic appetite-regulation studies, and gastric motility models. Comparative work alongside native GLP-1 and tirzepatide enables receptor-selectivity and biased-agonism characterization.
This compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.
Specifications
Compound Name: Semaglutide
Strength: 20mg
Purity: ≥ 99% (HPLC Verified)
Appearance: Lyophilized Peptide Powder
Format: Research Compound
Reconstitution: Suitable for laboratory assay preparation.
Notice
Provided as a reference material for scientific investigation only.
Product Specifications
| CAS Number | 910463-68-2 |
|---|---|
| Molecular Formula | C187H291N45O59 |
| Molecular Weight (g/mol) | 4113.58 |
| Amino Acid Count | 31 |
| Amino Acid Sequence | 31-residue GLP-1 receptor agonist analog with Aib at position 2 and Lys26 conjugated to γGlu-(AEEA)2-C18 diacid; C-terminal carboxylate (full sequence per COA). |
| Purity | 99% by HPLC COA available |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in bacteriostatic water; consult the product COA for specific solvent recommendations. |
| Storage Conditions | Store lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory protocol. |
For Research Use Only. Not for use in diagnostic, therapeutic, or human or animal in-vivo procedures. This product is sold exclusively for in-vitro laboratory research use. It is not a drug, dietary supplement, food, or cosmetic and has not been approved by the U.S. Food and Drug Administration for any use. Not for human or animal consumption.
